Reporting guideline · JAMIA 2026
CINEX
Clinical Information Extraction Guideline
A consensus-based reporting guideline for studies that extract information from clinical text, developed through a three-round Delphi study with international experts.
- 29
- reporting items
- 5
- dimensions
- 3
- Delphi rounds

The guideline at a glance
29 reporting items, grouped into five dimensions. Each item carries its rationale, the points to cover, and worked examples from the published Explanation & Elaboration document.
Information model
What is extracted, and the clinical and technical models that give it meaning.
5 itemsA1–A5Architecture
The task, the implementation, and the compute behind it.
5 itemsD1–D9Data
Where the texts come from, how they were split, and who they represent.
9 itemsAN1–AN5Annotation
How the reference standard was produced, and how reliable it is.
5 itemsO1–O5Outcome
Performance, validation, and what is available to others.
5 itemsWorking with CINEX
Guideline elements
All 29 items with rationale, reporting points and worked examples.
Browse elements →Digital form
Complete the checklist for your study and export it as PDF, Word or JSON.
Start filling →Publications
The guideline paper, the development protocol, and studies using CINEX.
View publications →ACCORD checklist
How the CINEX consensus process itself is reported, item by item.
View checklist →Citing CINEX
Reichenpfader D, Zaghir J, Cécilia-Joseph E, et al. The consensus-based CINEX guideline for reporting clinical information extraction studies. J Am Med Inform Assoc 2026;ocag136.